Some vaccines contain living infectious agents ; included in this group are those used against yellow fever and measles, as well as the Sabin oral polio vaccine.
These living agents have been weakened in the laboratory but still provoke the formation of specific antibodies.
Other vaccine contain killed infectious agents; included in this group are the whooping cough and Salk polio vaccines.
The killed microbes will not produce the disease, but they will stimulate production of specific antibodies against the same organism, thereby protecting the body from future infection.
Along similar lines, acquired immunity can be induced against certain microbial toxins that produce disease. Diphtheria and tetanus produce disease through their toxins.
Modified toxins, called toxoids, which are no longer poisonous, are used to induce the production of antibodies that will inactivate the poisons if the invading organism strikes.